There were four confirmed deaths resulting from the earthquake, including a child in Takatsuki who was crushed by a collapsing wall outside her elementary school. Flights at two of the airports in the Kansai region were temporarily suspended, but resumed hours later. Operations at the JXTG Nippon Oil & Energy's oil refinery in Osaka and various manufacturing plants in the Kansai region were suspended to check for damage. The Osaka Monorail reopened for service on 23 June, but was forced to suspend operations the following day due to the discovery of additional damage to the train cars. During the shutdown, passengers disembarked from trains and walked along the tracks, due to fears of aftershocks causing further damage. The earthquake disrupted train services, including the Shinkansen, during the morning rush hour but had resumed service six hours later, in time for the afternoon commute. Gas services were also stopped for over 112,000 households in Ibaraki and Takatsuki for several days, but was fully restored by 25 June. At least 170,000 homes in Osaka were initially under an electrical blackout, but power was restored later in the morning. Roof tiles and stone ornaments at homes and historic temples and shrines fell to the ground. As many as 450 people remained in public shelters a week after the earthquake. A total of 6,766 structures were found by government surveys to have sustained partial damage, primarily in Osaka Prefecture but also including several in Kyoto Prefecture, Nara Prefecture, and Hyōgo Prefecture. The earthquake caused the partial collapse of several buildings, as well as damage to underground water pipes that left residents without running water. Therefore, this event is case of joint movements on multiple faults. Shear movements on both of these buried faults contribute significantly to the total seismic moment of this earthquake.

Next, the activated reverse fault might have a relationship with the deeper segments of the Uemachi fault zone. The activated strike-slip fault was parallel to the Arima-Takatsuki fault zone (and Itami fault).

The later research shows that the earthquake source was case of geometrically complex faulting on at least two different faults. It was the first time a lower 6 was registered in Osaka Prefecture since 1923 when the government started to keep seismic records. The earthquake registered as 6 ('lower 6') on the shindo intensity scale, and the United States Geological Survey reported a magnitude of 5.5 M w. The Japan Meteorological Agency assigned an initial magnitude of M JMA5.9, which it later upgraded to M JMA 6.1 (moment magnitude of 5.6 M w). No tsunami waves were generated as a result of the earthquake. The earthquake triggered the national earthquake warning system, which set alarms approximately 3.2 seconds for the Osaka and Kyoto areas after the detection of seismic waves. Within the following week, a total of 40 strong aftershocks were detected by the Japan Meteorological Agency. It was felt strongly in northern Osaka and also affected parts of nearby Kyoto. The Great Hanshin earthquake of 1995 struck nearby Kobe with great intensity, causing thousands of deaths. Three of the region's fault zones (Arima-Takatsuki, Uemachi, and Ikoma) are located near the epicenter and are suspected to have caused the earthquake. The Kansai region sits atop several active faults, which can produce inland shallow earthquakes. Japan Standard Time on 18 June, with its epicenter in the Takatsuki area of northeastern Osaka, at a depth of approximately 13 kilometres (8.1 mi). Four people were killed, 15 serious injuries were reported, and 419 people had minor injuries. The earthquake struck during rush hour, disrupting train services for several hours, and also damaged water pipes and hundreds of homes. Shaking from the earthquake was felt strongly in the prefecture and the nearby metropolitan areas of Osaka and Kyoto, temporarily disrupting electrical and gas service to 170,000 homes and buildings.

The Japan Meteorological Agency reported a magnitude of 6.1 M j and an intensity of 6 lower on the shindo scale. The earthquake's epicenter was near Takatsuki and occurred at a depth of approximately 13 kilometres (8.1 mi). Japan Standard Time, an earthquake measuring 5.6 M w on the moment magnitude scale (preliminary 5.5 M w) struck in northern Osaka Prefecture, Japan.

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